Begins with an overview of immune-mediated eye disease, summarizing basic immunologic concepts, ocular immune responses and special topics in ocular immunology. Discusses the clinical approach to uveitis and reviews noninfectious (autoimmune) and infectious forms of uveitis, with an expanded section on viral uveitis and new material on infectious and noninfectious scleritis. Enhanced detection of infectious agents by immunologic and genetic methods and biologic therapeutics are detailed. Also covers endophthalmitis, masquerade syndromes, complications of uveitis and ocular aspects of AIDS. Upon completion of Section 9, readers should be able to: * Identify general and specific pathophysiologic processes that affect the structure and function of the uvea, lens, intraocular cavities, retina, and other tissues in acute and chronic intraocular inflammation * Differentiate and identify infectious and noninfectious uveitic entities * Choose appropriate examination techniques and relevant ancillary studies based on whether an infectious or noninfectious cause is suspected