Muco adhesive system was found to be a better alternative to the conventional oral route. These developed muco adhesive systems has several advantages which includes, reducing the level of toxicity, help to overcome the first pass metabolism, suitable for the drug which may reduce in the acidic pH of the stomach, shows a controlled release of drug, ease of application, and the formulation and evaluation of such systems does not have any complication. Based on these, muco adhesive system may be considered as one of the most important dosage form in the future pharmaceutical and health care sector.