This is a popular science book on physics, astronomy and related sciences, designed for a wider audience. It is written as a guide for a tour along the ladder of scales from the Universe as a whole to the microcosm. The main scales are the Universe, Solar System, the Earth, normal human size, atoms, and elementary particles. Exotic objects such as black holes and neutron stars are also considered, as well as the foundations of the scientific method, its connection with philosophy, and a story about how modern science arose. This book contains many useful illustrations. The basic concepts of physics are discussed: forces, fields, quantum phenomena, structure of matter, phase transitions, atoms, molecules, dark matter, and dark energy. And also galaxies, supernova explosions, the Sun, planets, exoplanets, black holes, neutron stars, white dwarfs, the possibility of space expansion of mankind. The book also discusses phenomena like rainbow, mirages, lightning, climate on Earth, as well as practical applications like nuclear and thermonuclear reactors, superconductivity and helium-3 mining on the Moon. This book has included the latest results.