Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, Volume 355 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.

• Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biology
• Offers a wide range of perspectives for basic and translational research
• Discusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications