Acute Pulmonary Embolism: A Challenge for Hemostasiology

Thrombophilia and thrombogenesis.- The molecular mechanisms of inherited thrombophilia.- Hypercoagulative syndrome: Molecular markers for the identification of cardiovascular patients at risk.- Clinical implications of the new understanding of thrombophilia.- The clinical syndrome of acute pulmonary embolism.- Mechanisms of ventilation-perfusion mismatch and hemodynamic alterations in acute and chronic pulmonary embolism.- Clinical course and prognosis of acute pulmonary embolism.- Clinical implications of a patent foramen ovale in patients with massive pulmonary embolism.- The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- MR-angiography in the diagnosis of pulmonary embolism.- Anticoagulation and fibrinolysis.- Anticoagulation.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.- Low molecular weight heparins — Pharmacological principles and indications in clinical practice.- Heparin-induced thrombocytopenia.- New developments in the thrombolytic therapy of venous thrombosis.- The risk of recurrent venous thromboembolic disease — implications for treatment.- A randomized trial of the effect of low molecular weight heparin vs. warfarin on mortality in the long-term treatment of proximal vein thrombosis.- Fibrinolysis.- Thrombolytic therapy in pulmonary embolism. Which patients should be treated, which regimen should be used?.- Thrombolytic treatment of pulmonary embolism: Life-saving option or unacceptable risk?.- Surgical treatment of acute pulmonary embolism.