In this issue of Gastroenterology Clinics, guest editor Dr. John A. Martin brings his considerable expertise to the topic of Advances in Endoscopy. Endoscopy has forever changed the fundamental nature of the clinical gastroenterologist’s practice, from one that was originally predominantly clinic-based, to one that, today, is largely driven by endoscopy. In this issue, top experts explore and celebrate the now numerous facets of diagnostic and therapeutic endoscopy that markedly benefit patients today and continually advance to empower the gastrointestinal endoscopist more and more, year by year.