47andhishandler,DianaBurnwood,areateamresponsibleforsomeofthemostruthless,efficientanduntraceableassassinationsacrosstheglobe.ButbeforetheywereoperativesoftheshadowyInternationalContractsAssociation,47andBurnwoodwereontheirownseparatepathsinlife-streetslinedwithblood,bulletsandrevenge.As14-year-oldDianabeginsamissiontotrackdownthepeoplewhokilledherparents,47isstrugglingtofreehimselfandhisfriend,6,fromthemysteriousInstitutewhichhasbredthemaskillerssincetheywerekids.WithastorythatstretchesfromtheheartlandofAmericatotheBerlinWall,LoneWolveswilltracethebirthofthelegendaryHitmanandthesecretpastofthewomanbehindhimwhopullsthestringandknowsjusthowhardtakingalifetrulyis.