This historical guidebook includes 366 places that are significant to American Indians and open to the public. The book is organized geographically and includes location information, maps, and color photographs as well as suggestions for further reading about the sites and an extensive bibliography.

Among the 279 authorities who know and revere these places and have written essays on them and on topics relating to them are William deBuys, Suzan Shown Harjo, Frederick E. Hoxie, Clara Sue Kidwell, Malinda Maynor Lowery, Rennard Strickland, and David Hurst Thomas. Tribal culture committees and tribal historians also contributed essays. Frances H. Kennedy, the editor and principal contributor, has written short entries on more than a hundred of the places.

The places covered in the book include: Ganondagan State Historic Site in New York Kituhwa Mound in North Carolina, Cahokia Mounds State Historic Site in Illinois, Crystal River Archaeological State Park in Florida, Effigy Mounds National Monument in Iowa, Devils Tower National Monument in Wyoming, Chaco Culture National Historical Park in New Mexico, Navajo National Monument in Arizona, Olompali State Historic Park in California, La Purisima Mission State Historic Park in California, Nez Perce National Historical Park in Idaho.