Louise Armstrong Holliday is the last person on Earth you'd expect to save the human race. But when she uncovers proof that her boss is an alien the color of lime jelly gone horribly wrong, and is at the center of a plot to destroy humanity, Louie decides to do exactly that. She begins a journey from her company's suburban Seattle office park to the old cities and castles of Eastern Europe. Along the way, Louie is attacked by flying books, overly-sensitive bat-crow monsters, and her own self-doubts. She must learn the truth about her closest friend, stand up to her boss, confront her oldest enemy, and make peace with her Aunt Emma, who annoys her in the way only true family can. She also has to rely on Buddy, the little blind mini-Schnauzer who saves her life twice-and really is from Mars.