Essentially, this dissertation evaluated some selected anti-corruption policies in Nigeria with particular focus on Edo State. In generating data for the study, a combination of survey and library and archival methods were utilized. Based on the investigation of this study, several grounded hypotheses were validated. First, the study revealed that weak institutional framework limits the effectiveness of anti-corruption policies in Nigeria. It was discovered that poor leadership commitment is a constraint to the effectiveness of anti-corruption policies. Furthermore, the study unveiled that over politicization and incessant political interferences inhibit the effectiveness of anti-corruption policies. In-addition, the study identified poor funding, inadequate monitoring and networking among security agencies, government failure to meet the needs of the citizenry, poor reportage of corrupt practices, and low commitment of bureaucrats as inhibitive factors for the effective performance of anti-corruption policies in Nigeria the study recommended that adequate funding, leadership commitment, provision of social welfare schemes will enhance their effectiveness.