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An Introduction to Human Molecular Genetics – Mechanisms of Inherited Diseases 2e

Autor JK Pasternak
en Limba Engleză Hardback – 14 iul 2005
An Introduction to Human Molecular Genetics Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been thoroughly incorporated into the text. The first part of the text introduces readers to the fundamentals of cytogenetics and Mendelian genetics. Next, techniques and strategies for gene manipulation, mapping, and isolation are examined. Readers will particularly appreciate the text's exceptionally thorough and clear explanation of genetic mapping. The final part features unique coverage of the molecular genetics of distinct biological systems, covering muscle, neurological, eye, cancer, and mitochondrial disorders. Throughout the text, helpful figures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text's same lucid and engaging style, and will find a wealth of new and expanded material that brings them fully up to date with a current understanding of the field, including: * New chapters on complex genetic disorders, genomic imprinting, and human population genetics * Expanded and fully revised section on clinical genetics, covering diagnostic testing, molecular screening, and various treatments This text is targeted at upper-level undergraduate students, graduate students, and medical students. It is also an excellent reference for researchers and physicians who need a clinically relevant reference for the molecular genetics of inherited human diseases.
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Specificații

ISBN-13: 9780471474265
ISBN-10: 0471474266
Pagini: 672
Dimensiuni: 218 x 287 x 36 mm
Greutate: 1.81 kg
Ediția:2nd Edition
Editura: Wiley
Locul publicării:Hoboken, United States

Public țintă

This textbook is written for advanced undergraduates, beginning graduates, and medical students. It is also appropriate for researchers and physicians as a quick yet thorough, clinically relevant reference for information about the molecular genetics of inherited human diseases.

Cuprins


Notă biografică

Dr. Jack J. Pasternak received his Ph.D. from Indiana University and is now Professor Emeritus at the University of Waterloo. He has authored or co-authored several textbooks, including Molecular Biotechnology: Principles and Applications of Recombinant DNA.

Descriere

Human molecular genetics is the field of study focused on the functions of the human genetic system in relation to inherited diseases. An Introduction to Human Molecular Genetics, Second Edition examines how human genes are discovered and how disease genes cause particular disorders.