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Animal Models of Cognitive Impairment

Editat de Edward D. Levin, Jerry J. Buccafusco
en Limba Engleză Hardback – 22 iun 2006
The costs associated with a drug’s clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications.
The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer’s, schizophrenia, and ADHD.
Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.
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Specificații

ISBN-13: 9780849328343
ISBN-10: 0849328349
Pagini: 394
Ilustrații: 43 b/w images and 12 tables
Dimensiuni: 156 x 234 x 26 mm
Greutate: 0.7 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Academic and Professional Reference

Cuprins

Introduction. Pharmacologic Models. Toxicologic Models. Mouse Genetic Models. Model Applications And Future Developments.

Notă biografică

Edward D. Levin, Jerry J. Buccafusco

Descriere

Animal models of cognitive function, including learning, memory, and attention, are critical for determining the neurobehavioral basis for cognition and for the development of new therapeutic treatments for cognitive impairment. Animal Models of Cognitive Impairment features an integrated approach that combines molecular and neurochemical approaches in translational models with behavioral and clinical applications. The text also discusses current research on genetic, lesion, pharmacological toxicant, and aging models. The book then explores the significance of this research to the treatment of various addictions and disorders such as stroke, autism, Alzheimer’s, schizophrenia, and ADHD.