Cantitate/Preț
Produs

Anti-HIV Bioadhesive Microencapsulated Vaginal Gel

Autor Arkendu Chatterjee, Benoy Brata Bhowmik, K. Gauthaman
en Limba Engleză Paperback – 7 iun 2012
The aim of this study was to develop and evaluate Zidovudine (AZT) loaded microparticulated bioadhesive vaginal gel (AZMBVG) in order to obtain a controlled-releasing, in order to obtain a controlled-release system for treatment of AIDS. AZT microparticle AZMCs was prepared by O/O single emulsion solvent evaporation method (II) and evaluated for encapsulation efficiency, drug loading, surface morphology and invitro drug release profiles and drug release mechanism and optimized. To achieve second objective, optimized AZMC4 were encompassed in bioadhesive gel to form AZMBVGs by cold mechanical method and compared with the bioadhesive vaginal gel (BVG1) without microcapsule. The optimized microcapsules were incorporated in bioadhesive gel prepared using different bioadhesive polymer evaluated the gel for the encapsulation efficiency, drug loading,invitro release profiles and drug release kinetics, spreadability, extrudibility, bioadhesion , vaginal irritancy and pharmacokinetics study by invivo methods by using New Zealand white female rabbit model. A comprehensive protocol, for the AZMBVG was developed successfully. Further research in this area will be significant outcome for AIDS
Citește tot Restrânge

Preț: 47085 lei

Preț vechi: 49563 lei
-5% Nou

Puncte Express: 706

Preț estimativ în valută:
9016 9752$ 7513£

Carte tipărită la comandă

Livrare economică 11-25 decembrie

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783659149986
ISBN-10: 3659149985
Pagini: 224
Dimensiuni: 152 x 229 x 13 mm
Greutate: 0.34 kg
Editura: LAP LAMBERT ACADEMIC PUBLISHING AG & CO KG
Colecția LAP Lambert Academic Publishing

Notă biografică

Mr.Arkendu Chatterjee M.Pharm, Ph.D.from University of North Bengal, West Bengal,India Research area of interest:Micro and Nanotechnology for vaginal Controlled drug delivery development.Having 15 research paper (national and international).Handle 17 research project.Financial assistance from AICTE and DST (India).Present research paper in USA 2010