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Antisense Research and Applications

Autor Crooke T. Crooke, Stanley T. Crooke, Bernard Lebleu
en Limba Engleză Hardback – 30 apr 1993
Antisense Research and Applications is a comprehensive review of oligonucleotide research covering molecular biological advances in this field, the current status of antisense drug research, and strategies for future research and therapeutic applications.
In bringing together the latest research from an array of authoritative scientists, Antisense Research and Applications provides an integrated conceptual basis for considering oligonucleotide therapeutics. Topics covered in the 32 chapters of this book include nucleic acid structure and function, antisense RNA, medicinal chemistry of oligonucleotides, analogs, pharmacokinetics and toxicology, and activities of current antisense drugs.
This volume addresses advances in a broad range of disciplines and is an excellent resource for basic researchers and applied investigators in pharmaceutical laboratories and in such fields as biochemistry and molecular biology.
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Specificații

ISBN-13: 9780849347054
ISBN-10: 084934705X
Pagini: 624
Ilustrații: 32 tables, 11 halftones and 8 equations
Dimensiuni: 178 x 254 x 44 mm
Greutate: 1.37 kg
Ediția:1
Editura: CRC Press

Cuprins

Introduction. Nucleic Acid Structure and Function. Antisense RNA. Medicinal Chemistry of Oligonucleotides. First Generation Analogs. Newer Analogs. Mechanisms of Action of Current Synthetic Oligonucleotides. Pharmacokinetics and Toxicology. Activities of Current Antisense Drugs. Index.