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Apoptosis: The Life and Death of Cells

Autor Christopher Potten, James Wilson
en Limba Engleză Paperback – 15 aug 2004
The concept of programmed cell death, or apoptosis, has exploded into a major scientific field of interest for cell biologists, oncologists, and many other biomedical researchers. Apoptosis occurs throughout the lifetime of most multicellular organisms. During development, for example, the selective death of cells is vital to remove tissue between the digits to produce fingers and toes. Apoptosis is also necessary to destroy cells that represent a threat to the integrity of the organism, for example cells infected by a virus. In many cancers the genes regulating apoptosis are defective, producing immortal, continuously proliferating cells. This book, first published in 2004, discusses the philosophical and technical difficulties in defining the moment of death for a cell, as well as the biological implications and significance of programmed cell death. Recent developments in the genetic control and interacting gene networks associated with apoptosis are presented. The book is written for advanced undergraduate and postgraduate students, and is highly illustrated to aid understanding.
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Specificații

ISBN-13: 9780521626798
ISBN-10: 052162679X
Pagini: 228
Ilustrații: 46 b/w illus. 10 colour illus. 8 tables
Dimensiuni: 178 x 254 x 12 mm
Greutate: 0.49 kg
Ediția:New.
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:New York, United States

Cuprins

1. Dead or alive; 2. How to die; 3. What to wear and who clears up the rubbish; 4. To reproduce or die; 5. The judge, jury, and executioner - the genes that control cell death; 6. Stem cells; 7. An in vivo system to study apoptosis: the small intestine; 8. Cell death in diverse systems; 9. Measuring levels of cell death.

Recenzii

'A compelling read for anyone interested in organismal development … This is a timely publication and one that will fill a much-needed niche on biologist's bookshelves.' Biologist

Descriere

This book, first published in 2004, is a comprehensive and accessible overview of apoptosis, the genetically programmed self-destruction of a cell.