Applying Genomic and Proteomic Microarray Technology in Drug Discovery
Autor Robert S. Matsonen Limba Engleză Paperback – 14 oct 2024
Updated and revised to reflect recent progress in the field, the second edition discusses:
- Expanded omics-driven applications, including the areas of metabolomics and chemical biology
- The commercialization of the microarray platform, with a historical perspective aimed at recognizing key technological developments
- Solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays
- Different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented
- The development of the gene expression microarray and representative applications
- The development of protein microarray technology, including its history and key applications
Microarrays remain an invaluable tool for omics-based research not only in drug discovery, but in the life sciences, in clinical research, and for diagnostic applications worldwide. This volume presents the current state of the art on the utility of this technology to solve a host of important biological problems.
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Specificații
ISBN-13: 9781032922072
ISBN-10: 1032922079
Pagini: 324
Ilustrații: 200
Dimensiuni: 156 x 234 mm
Greutate: 0.6 kg
Ediția:2
Editura: CRC Press
Colecția CRC Press
Locul publicării:Boca Raton, United States
ISBN-10: 1032922079
Pagini: 324
Ilustrații: 200
Dimensiuni: 156 x 234 mm
Greutate: 0.6 kg
Ediția:2
Editura: CRC Press
Colecția CRC Press
Locul publicării:Boca Raton, United States
Public țintă
Academic and Professional Practice & DevelopmentRecenzii
"This publication offers a detailed perspective and insight into the present and future uses of this technology"
Anticancer Research
"A basic reference on the benefits of microarray technology in drug discovery, this publication offers a detailed perspective and insight into the present and future uses of this technology."
Anticancer Research
Anticancer Research
"A basic reference on the benefits of microarray technology in drug discovery, this publication offers a detailed perspective and insight into the present and future uses of this technology."
Anticancer Research
Cuprins
Omics and Microarrays Revisited. Commercial Microarrays. Supports and Surface Chemistries. Arraying Processes. Gene Expression: Microarray-Based Applications. Protein Microarray Applications. Multiplex Assays. Index.
Notă biografică
Robert S. Matson is president and co-founder of QuantiScientifics, LLC. The company is involved in the commercialization of multiplexed assays for life science, clinical research, and in vitro diagnostics. Previously, Matson was involved in the research and development of microarray technologies, detection chemistries, as well as point-of-care devices for more than 17 years while at Beckman Coulter, Inc. He participated in the National Institute of Standards and Technology’s (NIST) Advanced Technology Program sponsored Genosensor Consortium and collaborated with Sir Edwin Southern on the development of an in situ oligonucleotide array synthesis platform for the corporation. Other work included development of the A2 MicroArray System, a microplate-based array platform for multiplexed micro-ELISA, which QuantiScientifics recently licensed for commercialization.
Descriere
Microarrays play an increasingly significant role in drug discovery. Updated and revised to reflect recent progress in the field, the second edition of this volume discusses omics-driven applications, the commercialization of the microarray platform, and solid-supports (substrates) and surface chemistries currently used in the creation of nuclei