" Are psoriasis and metabolic syndrome offshoots of the same root?" is a small exercise to make a scientific understanding of etiological association of the two processes. Although a good beginning, still lot of research is needed in this field. C-reactive protein, a marker of inflammation, can be used to sort out those psoriatic patients who are likely to benefit from therapy by biological agents and can also help to delineate those psoriatic patients who are at high risk of developing a metabolic syndrome.