Arrestins: Structure and Function in Vision and Beyond
Editat de Vsevolod V. Gurevichen Limba Engleză Paperback – 24 mar 2022
- 2023 PROSE Awards - Winner: Finalist: Biomedicine and Neuroscience: Association of American Publishers
- Links basic, translational and clinical research on arrestin and GPCR signaling proteins in the nervous system
- Features chapters on arrestins' vital signaling functions in brain health
- Includes unique sections on their use as potential therapeutic targets
- Covers both vision and non-vision arrestins
- Provides an overview for scientists new to the study of GPCRs and arrestins
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Specificații
ISBN-13: 9780323857567
ISBN-10: 0323857566
Pagini: 142
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0323857566
Pagini: 142
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE
Cuprins
1. History of Arrestins
2. Basic Principles of G Protein-Coupled Receptor signaling
3. Structural Basis of Arrestin-GPCR Interactions
4. Non-Visual Arrestins: Mechanisms of Arrestin Activation and Arrestin-Dependent Signaling
5. Mechanisms of Arrestin-Mediated JNK Activation
6. Mechanisms of Arrestin-Dependent Facilitation of ERK Signaling
7. Visual Arrestins in Photoreceptor Function and Visual Disorders
8. Arrestins in GPCR Endocytosis
9. Arrestins as therapeutic Targets
10. Introducing Bias into GPCR-Dependent and Independent Arrestin Signaling by Protein Engineering
2. Basic Principles of G Protein-Coupled Receptor signaling
3. Structural Basis of Arrestin-GPCR Interactions
4. Non-Visual Arrestins: Mechanisms of Arrestin Activation and Arrestin-Dependent Signaling
5. Mechanisms of Arrestin-Mediated JNK Activation
6. Mechanisms of Arrestin-Dependent Facilitation of ERK Signaling
7. Visual Arrestins in Photoreceptor Function and Visual Disorders
8. Arrestins in GPCR Endocytosis
9. Arrestins as therapeutic Targets
10. Introducing Bias into GPCR-Dependent and Independent Arrestin Signaling by Protein Engineering