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Atomic Force Microscopy in Molecular and Cell Biology

Editat de Jiye Cai
en Limba Engleză Hardback – 15 noi 2018
The book addresses new achievements in AFM instruments – e.g. higher speed and higher resolution – and how AFM is being combined with other new methods like NSOM, STED, STORM, PALM, and Raman. This book explores the latest advances in atomic force microscopy and related techniques in molecular and cell biology. Atomic force microscopy (AFM) can be used to detect the superstructures of the cell membrane, cell morphology, cell skeletons and their mechanical properties. Opening up new fields of in-situ dynamic study for living cells, enzymatic reactions, fibril growth and biomedical research, these combined techniques will yield valuable new insights into molecule and cell biology. This book offers a valuable resource for students and researchers in the fields of biochemistry, cell research and chemistry etc.
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Specificații

ISBN-13: 9789811315091
ISBN-10: 9811315094
Pagini: 262
Ilustrații: XIII, 235 p. 136 illus., 109 illus. in color.
Dimensiuni: 155 x 235 x 20 mm
Greutate: 0.54 kg
Ediția:1st ed. 2018
Editura: Springer Nature Singapore
Colecția Springer
Locul publicării:Singapore, Singapore

Cuprins

Principles of atomic force microscopy.- Atomic force microscopy-based single molecule force spectroscopy for biological applications.- Single molecule in situ detection on cell membrane and label molecule distributions using AFM/NSOM.- AFM imaging-force spectroscopy combination for molecular recognition at the single-cell level.- High resolution imaging of cells using atomic force microscopy.- The hyphenated technique of high speed atomic force microscopy and super resolution optical detection system.- AFM/Raman spectrum based imaging system and its application in single molecule detection.- Observing drug interactions with cell at nanoscale using atomic force microscopy.- In situ measuring mechanical properties of normal and disease cells.- High resolution AFM and its applications in molecular and cell biology.

Notă biografică

Dr. Jiye Cai is a Professor at Department of Chemistry, Jinan University, Guangzhou, China

Textul de pe ultima copertă

The book addresses new achievements in AFM instruments – e.g. higher speed and higher resolution – and how AFM is being combined with other new methods like NSOM, STED, STORM, PALM, and Raman. This book explores the latest advances in atomic force microscopy and related techniques in molecular and cell biology. Atomic force microscopy (AFM) can be used to detect the superstructures of the cell membrane, cell morphology, cell skeletons and their mechanical properties. Opening up new fields of in-situ dynamic study for living cells, enzymatic reactions, fibril growth and biomedical research, these combined techniques will yield valuable new insights into molecule and cell biology. This book offers a valuable resource for students and researchers in the fields of biochemistry, cell research and chemistry etc.

Caracteristici

Introduces the latest development of atomic force microscopy and related high techniques in the molecular and cell biology Summarizes the new progress regarding high-resolution imaging for membrane structure and nanomechanical measurements for cell Provides examples to illustrate how to achieve high resolution in AFM experiments