The objective of this work was to determine the relationship between quantum mechanisms and their effect on photosynthetic biological models applied to atomic genetic evolution in the p53 gene of Homo sapiens. Mutations were performed in the p53 gene following evolutionary conservation parameters, especially in the 42 CpG points that are related to mutations influenced by ultraviolet radiation. These mutated sequences were compared with sequences of the same gene in several primates, using the mouse as a comparison "Outgroup". Neighbor Joining (NJ) trees and correspondence analyses were constructed with VISTA and PAUP. Genetic distances were calculated with MEGA. The results revealed that the 6 mutations in the p53 gene of Homo sapiens cause genetic divergence. It suggests a direct relationship between quantum effects and evolution. It is concluded that quantum mechanisms may play a role in genetic evolution, in relation to the photoelectric effect, Frenkel's exiton, De Förster Theory and p53 gene mutations. This supports the hypothesis that quantum effects can influence evolutionary processes at the molecular and genetic level.