- Lawrence Osborne
- Mary Pope Osborne
- Perri O'Shaughnessy
- Pat O'Shea
- Osho
- Martha Ostenso
- Emily Oster
- Alexander Osterwalder
- John Ostrander
- Ronnie O'Sullivan
- Niyi Osundare
- Peter Oswald
- Thomas G. Otte
- Géza Ottlik
- Catherine M. Otto
- Yotam Ottolenghi
- Otto Ludwig
- Ouida
- P. D. Ouspensky
- Dennis Overbye
- Richard Overy
- Robert Owen
- Daniel Owen
- Ruth Owen
- Laura Owen
- Owen Johnson
- Rochelle Owens
- Elsie J. Oxenham
- Ferdinand Oyono
- Amos Oz
- Cynthia Ozick
- Steven Ozment
- Corina Ozon
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