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Azetidine Synthesis

Autor Navjeet Kaur
en Limba Engleză Paperback – sep 2025
Azetidine Synthesis offers a comprehensive exploration of various methods for the synthesis of azetidines, a class of heterocyclic compounds with diverse applications. Specifically, the significance of azetidine synthesis has grown largely due to the importance of these molecules as constituents of antibiotics. Chapters cover different synthetic pathways, starting with the general synthesis of azetidines and progressing to specific methods using various starting materials. From the copper-catalyzed synthesis of azetidines from nitrones to the synthesis from isoxazoles, oxazines, and diazo compounds, each chapter delves into the unique strategies and mechanisms involved. Rhodium-catalyzed approaches, cycloaddition reactions of imines to carbonyl compounds, and the use of isocyanides and isocyanates for azetidine synthesis are discussed in detail. The book also explores photochemical methods for azetidine synthesis, including the photochemical synthesis of fused azetidines. By providing a comprehensive overview of diverse synthetic routes to azetidines, this book serves as a valuable resource for researchers and practitioners in the field of organic chemistry, offering insights into the versatility and potential applications of these important heterocyclic compounds.

  • Presents many different methods for the synthesis of azetidines in clear, coherent detail
  • Offers a comprehensive and detailed description of heterocycle synthesis
  • Examines the most up-to-date information in this fast-moving field, covering important growth areas extensively
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Specificații

ISBN-13: 9780443403507
ISBN-10: 0443403503
Pagini: 300
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Cuprins

1. Synthesis of azetidines
2. Synthesis of azetidines from azides and cyanides
3. Synthesis of azetidines from aziridines and epoxides
4. Copper-catalyzed synthesis of azetidines from nitrones
5. Synthesis of azetidines from isoxazoles and oxazoles
6. Synthesis of azetidines from oxazines and isoxazoloxazines
7. Synthesis of azetidines from diazo compounds
8. Rhodium-catalyzed synthesis of azetidines from diazo compounds
9. Synthesis of azetidines by cycloaddition of imines to carbonyl compounds using triethylamine
10. Synthesis of azetidines by cycloaddition of imines to carbonyl compounds using lithium reagents
11. Synthesis of azetidines from isocyanides
12. Synthesis of azetidines from isocyanates
13. Photochemical synthesis of azetidines
14. Photochemical synthesis of fused azetidines