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Basic Pharmacology: Understanding Drug Actions and Reactions: Pharmacy Education Series

Autor Maria A. Hernandez, Ph.D., Appu Rathinavelu, Ph.D.
en Limba Engleză Hardback – 14 feb 2006
Intended for use in an introductory pharmacology course, Basic Pharmacology: Understanding Drug Actions and Reactions provides an in-depth discussion of how to apply the chemical and molecular pharmacology concepts, a discussion students need for more advanced study. The textbook introduces the principles of chemistry and biology necessary to understand drug interactions at the cellular level. The authors highlight chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and elimination. The book begins with a review of chemical principles as they apply to drug molecules, focusing mainly on those for commonly prescribed drugs. The authors use drug structures to illustrate the chemical concepts learned in general and organic chemistry courses. They cover the dynamics of receptors in mediating the pharmacological effects of drugs. They clarify theories, drawn from the scientific literature, which explain drug-receptor interactions and the  quantitative relationship between drug binding and its effects at the cellular level.
The authors’ extensive use of drug structures for teaching chemical and molecular pharmacology principles, and their emphasis on the relevance of these principles in future professional life makes this book unique. It provides the framework for better understanding of advanced pharmacology and therapeutics topics. Blending medicinal chemistry and  pharmacodynamics aspects, this textbook clearly elucidates the essential concepts that form the cornerstone for further work in pharmacology.
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Specificații

ISBN-13: 9781587161605
ISBN-10: 1587161605
Pagini: 388
Ilustrații: 277 b/w images and 34 tables
Dimensiuni: 156 x 234 x 25 mm
Greutate: 0.69 kg
Ediția:1
Editura: Taylor & Francis
Colecția Routledge
Seria Pharmacy Education Series

Locul publicării:Oxford, United Kingdom

Public țintă

Undergraduate

Cuprins

Structurally Non-Specific Drugs. Structurally Specific Drugs. Chemical Approaches to the Treatment of Cancer. Tutorial Examples. Problems. Drug Administration. Drug Absorption. Drug Distribution. Drug Elimination. Phase I Metabolic Reactions. Phase II Metabolic Reactions. Prodrugs. Drug Interactions. Clinical Correlation. Tutorial Example. Problems. References. Drug Receptors and Pharmacodynamics. Drug Induced Inhibition. Modes of Receptor Activation. Dose-Response Curves. Receptor Regulation. Receptor Signaling and Second Messenger Systems. Clinical Correlation.

Notă biografică

Maria A. Hernandez Ph.D., Ph.D. Rathinavelu

Descriere

Written as an introductory pharmacology text, Basic Pharmacology: Understanding Drug Actions and Reactions provides the in-depth discussion of the chemical and molecular pharmacology fundamentals that pharmacy students require to move on to more advanced study. The book covers the principles of chemistry and biology necessary to understand drug action at the cellular level. It emphasizes the chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and interactions. The book effectively explains chemical and molecular pharmacology principles with extensive use of model drug structures. Written as an introductory pharmacology text, Basic Pharmacology: Understanding Drug Actions and Reactions provides the in-depth discussion of the chemical and molecular pharmacology fundamentals that pharmacy students require to move on to more advanced study. Employing the extensive use of model drug structures, the authors effectively explain chemical and molecular pharmacology principles. The book covers the principles of chemistry and biology necessary to understand drug action at the cellular level. It emphasizes the chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and interactions.