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Behavioral Study of 'Non-Opioid' Tolerance

Autor Merab G Tsagareli, Nana Tisklauri
en Limba Engleză Paperback – 20 feb 2012
Pain is a response of the body to the action of injuring stimuli. Notwithstanding an unpleasant experience, it appears to be an important component of the defence system of the organism and a permanent regulator of homeostatic reaction. The organism's reaction to pain is a multi-component one and involves sensory-discriminative, emotional-affective and cognitive characteristics. Clinically, neuropathic pain is characterised by spontaneous ongoing or shooting pain and evoked amplified pain responses after nocuous or innocuous stimuli. The study of pain, therefore, and search for the treatment strategies have a paramount role in modern neurobiology. Numerous anatomy-physiological studies have revealed a number of brain structures involved in the shaping of pain and endogenous analgesia. This book presents and examines current research discovered in a behavioural study of 'non-opioid' tolerance.
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Specificații

ISBN-13: 9781621000334
ISBN-10: 1621000338
Pagini: 115
Ilustrații: Illustrations
Dimensiuni: 155 x 226 x 7 mm
Greutate: 0.21 kg
Editura: Nova Science Publishers Inc

Cuprins

Introduction; Pain & Nociception; Ascending Pain Signal Pathways; Downstream Modulation Of Pain; Tolerance To Opioid Drugs; Periaqueductal Grey Matter; Non-Opioid Analgesics Induced Tolerance; Comparison of the Effects of Tolerance in Juvenile & Adult Rats; The Central Nucleus of Amygdala is Involved in Tolerance to the Antinociceptive Effect of NSAIDs; Tolerance Induced by Non-Opioid Analgesics; Microinjected into Periaqueductal Grey Matter.