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Beta Cells

Editat de Sarah E. Gallagher
en Limba Engleză Hardback – 23 mai 2011
Beta cells or ß-cells, are a type of cell in the pancreas in areas called the islets of Langerhans. They make up 65-80% of the cells in the islets. Pancreatic B-cell is the only cell type that produces insulin to regulate glucose metabolism in the body. The insufficiency of insulin-producing B-cells results in dysregulation of blood glucose control, termed as type 1 diabetes. This book presents current research from across the globe in the study of Beta-cells, including the induction of pancreatic cancer cell death by elevated concentrations of extracellular zinc; the role of Rab GTPases and their effectors in the insulin secretory pathway of the pancreatic beta cell; In vivo reprogramming of pancreatic A-cells into B-like cells; and the role of glucocortoids, exercise and glucolipotoxicity with regard to stress and pancreatic B-cell function.
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Specificații

ISBN-13: 9781617612121
ISBN-10: 161761212X
Pagini: 176
Ilustrații: tables & charts
Dimensiuni: 179 x 262 x 17 mm
Greutate: 0.53 kg
Ediția:New.
Editura: Nova Science Publishers Inc

Cuprins

Stress & Pancreatic ß Cell Function: Role of Glucocortoids, Exercise & Glucolipotoxicity; The Synergistic Effect of ß Cell Replacement & Immunotherapy on the Treatment of Type 1 Diabetes; Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes & ß Cell Dysfunction in Zucker Diabetic Fatty Rats; Diabetes Mellitus: An Opportunity for Therapy with Regenerative Medicine?; Behind Beta Cell Glucotoxicity: A Pivotal Role of Glycoxidative Damage?; Induction of Pancreatic Cancer Cell Death by Elevated Concentrations of Extracellular Zinc; Rab GTPases Control Membrane Recycling in the Pancreatic Beta Cell; In Vivo Reprogramming of Pancreatic ?-cells into ß-like Cells; Studies of Toxin Resistant Beta-Cells: Lessons for the Chemotherapy?; Renin-Angiotensin System & Diabetes.