Bioactive Spin Labels de Renat I. Zhdanov

Bioactive Spin Labels

Renat I. Zhdanov

en Limba Engleză Paperback – 14 mai 2012

Bioactive Spin Labels is a collection of contributions by leading experts on nitroxyl radicals and their application in biomedicine. These compounds are used as side specific contrast agents for in-vivo EPR techniques. Their potential as drugs is investigated. Bioactive Spin Labels is a must for researchers in bioorganic chemistry, pharmacology and biomedicine.

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Cuprins

Spin-Labeled Medicines: Enzymes, Biomembranes and Possible Pharmaceuticals. An Overview.- Nitroxyl Radicals and Non-Radical Reactions of Free Radicals.- Triacetonamine in the Chemistry of Nitroxyl Radicals.- Catalysis of Redox Processes by Nitroxyl Radicals.- Biomembrane Reactions of Nitroxyl Radicals.- Relaxation Processes Involving Nitroxyl Radicals in Molecular Biology.- Investigations on Spin Exchange in Nitroxyls by the Method of Continuous Saturation of EPR Spectra.- Spin Exchange Components in Nitroxyl Biradicals EPR Spectra.- Investigation of Spin Labels and Probes by Millimeter Band EPR.- Analysis of Spin Label Slow Motions Based on Simulating 2-mm Band EPR Spectra.- Synthesis and Properties of Spin-Labeled Phospholipids.- Spin-Labeled Phospholipids for Protein-Lipid Interactions.- Spin-Labeled Organophosphorus Compounds.- Spin-Labeled Close Analogs of Sugars and Nucleosides.- Spin-Labeling Study of the Structure and Function of Leucine Aminopeptidae.- Photoaffinity Spin Labeling.- The Toxicity of Aminoxyl Radicals.- Nitroxyl Radicals for Cancer Chemotherapy.- Spin Labeling Study of Platelet Plasma Membrane and Nitroxyl Aggregation Inhibitors.- Anti-Ischemic Effect of 1-Hydroxy Derivatives of Nitroxyl Bioantioxidants.- Spin Probes for the Study of Intact and Cancer Cell Membranes.- Pharmacokinetics of Nitroxyl Radicals.- Computer-Assisted Evaluation of Nitroxyl Radical Effect on Biological Activity.- Aminoxyl Radicals as MRI Contrast Agents.- Aminoxyl Spin Labels in Clinical Analysis.- Applications of Spin-Label Techniques at High Pressures.