Biochemistry and Function of Sterols de Edward J. Parish

Biochemistry and Function of Sterols

Edward J. Parish

W. David Nes

Leading international scientists bring current and developing topics in sterol research together in Biochemistry and Function of Sterols. The authors are experts in each major area of sterol research-medicine, biochemistry, chemistry, and agriculture. Each chapter features the current state of research as well as new and developing research topics. Throughout the volume the focus is on the major and expanding areas of sterol biochemistry and function of sterols in all classes or organisms. The broad scope of this work embraces many disciplines and will be of interest to a variety of researchers, students, and lay people. Professors will find Biochemistry and Function of Sterols an excellent choice as a textbook for courses on steroid, lipid, or plant biochemistry.

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Cuprins

Inhibitors of 2,3-Oxidosqualene Cyclase as Tools for Studying the Mechanism and Function of the Enzyme, L. Cattel and M. Ceruti, Aromatase Inhibitors, J. O'Neal Johnston, Variability of Metabolism and Function of Sterols in Insects, J.A. Svoboda, Oxysterols and Apoptosis: Evidence for Gene Regulation Outside the Cholesterol Pathway, E.B. Thompson and S. Ayala-Torres, Tracing Steroid Synthesis in Plants, H.W. Groeneveld, Biochemistry and Molecular Biology of Sterol Synthesis in Saccharomyces cerevisiae, N.D. Lees, M. Bard, and D.R. Kirsch, 19-Noraldosterone, Y. Takeda, Enzymology of Phytosterol Transformations, W.D. Nes and M. Venkatramesh, Isoprenoid Biosynthesis in Plants: Carbon Partitioning Within the Cytoplasmic Pathway, J.D. Newman and J. Chappell, Mevalonate Biosynthesis in Plants, T.J. Bach, A. Boronat, N. Campos, A. Ferrer, and K.-U. Vollack, Lanosterol Analogs: Dual-Action Inhibitors of Cholesterol Biosynthesis, L.L. Frye and D.A. Leonard, Biochemistry and Function of Nematode Steroids, D.J. Chitwood, Occurrence, Biosynthesis, and Putative Role of Ecdysteroids in Plants, J.H. Adler and R.J. Grebenok, Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity by Side-Chain Oxysterols and Their Derivatives, E.J. Parish, S.C. Parish, and S. Li, Biological Effects of Brassinosteroids, C. Brosa, Vitamin D: A Hormonal Regulator of the cAMP Signaling Pathway, J.P. Berg and E. Haug, Protein Isoprenylation in Plants, S.K. Randall and D.N. Crowell, Chemical Modulation of Activity in Steroidal Estrogens, E. Palomino, Use of Sterol Mutants as Probes for Sterol Functions in the Yeast, Saccharomyces cerevisiae, L.W. Parks, J.H. Crowley, F.W. Leak, S.J. Smith, and M.E. Tomeo, Integration of the Metabolic Pathways of Steroids, Carotenoids, and Retinoids, A.M. Gawienowski, Index