Biochemistry of Antibodies
Autor R. Nezlinen Limba Engleză Paperback – 19 mar 2012
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Specificații
ISBN-13: 9781468417937
ISBN-10: 1468417932
Pagini: 404
Ilustrații: XIII, 381 p.
Dimensiuni: 152 x 229 x 21 mm
Greutate: 0.54 kg
Ediția:Softcover reprint of the original 1st ed. 1970
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States
ISBN-10: 1468417932
Pagini: 404
Ilustrații: XIII, 381 p.
Dimensiuni: 152 x 229 x 21 mm
Greutate: 0.54 kg
Ediția:Softcover reprint of the original 1st ed. 1970
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
I. Quantitative Methods for Determination of Antibodies.- Heidelbergern Quantitative Precipitation Method.- Quantitative Determination of Antibodies with the Aid of Immunoadsorbents.- Equilibrium Dialysis for the Quantitativ Measurement of the Hapten—Antibody Reaction.- Fluorescence Methods for Antibody Determination.- Literature Cited.- II. Isolation of Pure Antibodies.- Nonspecific Methods.- Specific Methods.- Isolation of Antibodies with the Aid of Fixed Antigens (Synthetic Immunoadsorbents).- Literature Cited.- III. Properties of Antibodies.- The Chief Types of Immunoglobulins.- Size and Shape of Molecules.- Molecular Weight.- Electrophoretic Properties.- Optical Properties.- Chemical Properties.- Valence of Antibodies.- Antigen Properties.- Heterogeneity of Antibodies.- Literature Cited.- IV. The Structure of Antibodies.- Fragments Obtained by Proteolytic Cleavage of Immunoglobulins.- Subunits and Peptide Chains Obtained by Chemical Treatment of Molecules of Immunoglobulins and Antibodies.- The Antibody Binding Site.- Literature Cited.- V. Antibody Biosynthesis.- The Fate of Antigen.- In Which Organs and Cells Are Antibodies Synthesized?.- Antibody-Synthesizing Cells.- RNA Synthesis in Lymphoid Cells during Antibody Synthesis.- Attempts to Induce Antibody Synthesis by RNA Fractions Isolated from Lymphoid Tissue of Immune Rabbits.- Dynamics of Antibody Synthesis.- In Vitro Antibody Synthesis.- Participation of Ribosomes in the Biosynthesis of Antibodies. Cell Free Systems Polyribosomes.- Inhibitors of Antibody Synthesis.- Literature Cited.- VI. Genetic Aspects of Antibody Synthesis.- Effect of Hereditary Factors on Synthesis of ?-Globulins and Antibodies.- Genetically Controllable Antigenic Determinants of Immunoglobulins (Allotypes).- Genes Controlling AntibodySynthesis.- Synthesis of DNA by Lymphoid Cells and Its Stimulation.- Literature Cited.- VII. Theory of Antibody Synthesis.- Template Theory of Antibody Synthesis.- Theory of the Pre-existence of Information for Antibody Specificity.- Theory of Repression—Derepression.- Evolutionary Aspects of Antibody Synthesis.- Literature Cited.