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Bioinformatics

Autor Hamid D. Ismail
en Limba Engleză Paperback – 13 mar 2025
Bioinformatics: A Practical Guide to NCBI Databases and Sequence Alignments provides the basics of bioinformatics and in-depth coverage of NCBI databases, sequence alignment, and NCBI Sequence Local Alignment Search Tool (BLAST).
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Specificații

ISBN-13: 9781032128740
ISBN-10: 1032128747
Pagini: 456
Dimensiuni: 210 x 280 mm
Greutate: 0.87 kg
Editura: Taylor & Francis Ltd.

Notă biografică

Hamid D. Ismail earned his Ph.D. and M.Sc. in computational science from North Carolina Agricultural and Technical State University, USA, and Doctor of Veterinary Medicine (DVM) and Applied Diploma in Statistics and Programming from the University of Khartoum, Sudan. He has worked as an adjunct professor, bioinformatics specialist, bioinformatics tool developer, senior scientist, statistician, and database consultant with several institutions. He is currently a Ph.D. Research Associate at North Carolina Agricultural and Technical State University. Dr. Ismail is a published author in bioinformatics, statistics, machine learning, and bio-science, and hehas developed a number of bioinformatics desktop and web-based applications. He is also a reviewer for a number of academic journals.

Cuprins

Sequencing and Raw Sequence Data Quality Control, Nucleic acids, Sequencing, Sequencing depth and read quality, FASTQ files, FASTQ read quality assessment, Preprocessing of the FASTQ reads, Mapping of sequence reads to the reference genomes, Introduction to sequence mapping, Read mapping, Read sequence alignment and aligners, Manipulating alignments in SAM/BAM files, Reference-guided genome assembly, De novo Genome Assembly, Introduction to De Novo genome assembly, Examples of De Novo assemblers, Genome Assembly Quality Assessment, Variant Discovery, Introduction to genetic variations, Variant calling programs, Visualizing variants, Variant annotation and prioritization, RNA-seq data analysis, Introduction to RNA-seq, RNA-seq data applications, RNA-seq data analysis workflow, Chromatin Immunoprecipitation sequencing, Introduction to chromatin immunoprecipitation, ChIP sequencing, ChIP-seq analysis workflow, Targeted Gene Metagenomic Data Analysis, Introduction to metagenomics, Analysis workflow, Data Analysis with QIIME2, Shotgun metagenomic data analysis, Introduction, Shotgun metagenomic analysis workflow


Recenzii

Bioinformatics is a necessary text that will help researchers/students gain background knowledge and understand the usage of NCBI databases. It is well suited for audiences who do not have a bioinformatics background as it defines what genomic data is and the fundamentals of the sequence alignment. It also thoroughly explains how to use NCBI tools to retrieve the researchers' genomic data of interest.
-- Roshonda Jones, Senior Bioinformatics Scientist, Nom Nom