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Biophysical Techniques in Drug Discovery: Drug Discovery, cartea 61

Contribuţii de Schon, Arne, Sciara, Giuliano, Andrew Scott
en Limba Engleză Hardback – 30 noi 2017
Biophysical techniques are used in many key stages of the drug discovery process including screening of new ligands for a certain receptor, characterisation of a drug mechanism and validation of data from biochemical and cellular assays. This title, with contributions from both academia and industry, brings together the different elements of biophysical techniques within drug discovery in a single volume. Topics covered include the characterisation of integral membrane proteins and their interactions with drugs, G protein-coupled receptors and important developments in the field such as improvement in electron microscopy resolution.
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Specificații

ISBN-13: 9781782627333
ISBN-10: 1782627332
Pagini: 300
Dimensiuni: 156 x 234 x 26 mm
Greutate: 0.64 kg
Editura: Royal Society Of Chemistry
Seria Drug Discovery


Textul de pe ultima copertă

Biophysical techniques are used in many key stages of the drug discovery process including in screening for new receptor ligands, in characterising drug mechanisms, and in validating data from biochemical and cellular assays.
This book provides an overview of the biophysical methods applied in drug discovery today, including traditional techniques and newer developments. Perspectives from academia and industry across a spectrum of techniques are brought together in a single volume. Small and biotherapeutic approaches are covered and strengths and limitations of each technique are presented. Case studies illustrate the application of each technique in real applied examples. Finally, the book covers recent developments in areas such as electron microscopy with discussions of their possible impact on future drug discovery.
This is a go-to volume for biophysicists, analytical chemists and medicinal chemists providing a broad overview of techniques of contemporary interest in drug discovery.

Descriere

With perspectives from academia and industry across a spectrum of techniques, this is a go-to volume for biophysicists, analytical chemists and medicinal chemists looking for a broad overview of techniques of contemporary interest in drug discovery.