After a tragedy that changed his life forever, including turning him into a werewolf, Jeremy Walker traveled around the United States hunting monsters of all kinds. On a recent hunt in mexico, he meets Sasha Grant - a homeless girl running from a dark past. Together they stop a group of Chupacabras terrorizing a farm and return to Jeremy's trainer only to find him murdered. Full of rage, he hunts the werewolf that killed his girlfriend and maybe his trainer only to find out a much bigger threat is brewing. Something that threatens the entire world. With the help of some friends, Jeremy and Sasha take on an ancient vampire bent on releasing monsters capable of wiping humanity off the face of the Earth.