This book tells you how brilliant ideas and inventions can be transformed into innovations and breakthroughs which make a real impact, and analyses why others fail. In a turbulent and fast-changing world we need innovations and breakthroughs to advance our wellbeing and achieve a sustainable society. Together with our international network of leaders, entrepreneurs and scholars, we present a wide range of case studies in which we examine the mechanisms that lead to genuine breakthroughs. We look at the worlds of business, philanthropy, diplomacy, economics, investing, geopolitics, media, agriculture, logistics, technology and healthcare. These fascinating studies and interviews reveal how innovations and breakthroughs succeed or fail.