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Calcium Binding Lysozymes

Autor E. A. Permiakov, Ludmilla A. Morozova-Roche
en Limba Engleză Hardback – 15 ian 2013
In this book, the authors describe an important class of calcium binding lysozymes that are evolutionarily related to the lysozyme superfamily and the lactalbumins. The authors take the reader through a journey from the evolution, then the structure and properties of the calcium binding lysozymes. They discuss new unique protein folding pathways with local co-operative, close related folding modes that exhibit multiple folding pathways which are not properties of the lactalbumins or non calcium binding lysozymes. They comprise one of the most diverse group of examples in protein folding. In addition this protein class, especially equine lysozyme, shows peculiar amyloid assembly properties that are not common with other fibril forming proteins. It is one of the first shown to form ring shaped amyloids and other complexes in vitro. Lastly equine lysozyme forms complex with oleic acid, a unique form ELOA, which contributes to the family of the human and bovine lactalbumin analogues HAMLET and BAMLET.
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Specificații

ISBN-13: 9781620817551
ISBN-10: 1620817551
Pagini: 171
Ilustrații: Illustrations
Dimensiuni: 183 x 261 x 16 mm
Greutate: 0.5 kg
Editura: Nova Science Publishers Inc

Cuprins

Preface; Introduction; Calcium in biological systems; Anatomy of calcium binding lysozymes; Physiology of calcium binding lysozymes; Dynamics and folding of calcium binding lysozymes; Kinetic intermediate states of lysozymes; Pathology of calcium binding lysozymes; Theraputic properties of calcium-binding lysozymes; Concluding remarks; References; Index.