Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance
Editat de Huiping Liu, Justin Durla Lathiaen Limba Engleză Hardback – 8 sep 2016
The book includes contributions from leading, worldwide experts in the field, helping readers embrace new hope in their quest to eradicate cancer with emerging clinical trials on treating cancer stem cells in combination with other therapies.
- Provides an authoritative and complete overview of cancer stem cells
- Includes comprehensive coverage of current therapeutic strategies targeting cancer stem cells
- Deepens a reader’s technical expertise in cancer stem cell biology
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Specificații
ISBN-13: 9780128038925
ISBN-10: 0128038926
Pagini: 542
Dimensiuni: 191 x 235 x 49 mm
Greutate: 1.29 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0128038926
Pagini: 542
Dimensiuni: 191 x 235 x 49 mm
Greutate: 1.29 kg
Editura: ELSEVIER SCIENCE
Public țintă
Graduate students, postdocs, and principal investigators in both academia and industry within the fields of cancer research, pharmaceutical science, molecular biology, and geneticsCuprins
Foreword by Jane Visvader and Stanton GersonSection I. CSC Overview and Methodology
1. Introduction: Cancer Stem Cells Siddhartha S. Mitra, Joy He, Rogelio Esparza, Gregor Hutter, Samuel H. Cheshier and Irving Weissman
2. Overview: Cancer Stem Cell Self-RenewalMaider Zabala, Neethan A. Lobo, Dalong Qian, Linda J. van Weele, Diane Heiser and Michael F. Clarke
3. Enrichment and Interrogation of Cancer Stem CellsAwad Jarrar, Anastasia Chumakova, Masahiro Hitomi, Justin Lathia
Section II. CSCs in Representative Organ systems
4. Critical Updates to the Leukemia Stem Cell ModelYogen Saunthararajah
5. Breast cancer stem cells and the move toward high resolution stem cell systemsBenjamin T. Spike
6. Lung Cancer Stem Cells: Drivers of Genetically and Histologically Complex DiseaseChristine M. Fillmore and Carla F. Kim
7. Colorectal cancer stem cellsSumaiyah Rehman, Jennifer Haynes, Evelyne Lima-Fernandes, Akshita Puri, Andrew Haller, Cherry Leung, Lauren Agro, Yadong Wang, and Catherine A. O’Brien
8. Targeting Bladder Cancer Stem Cells: One-Step Closer To The Clinic?Antonina Kurtova and Keith Syson Chan
9. Cancer Stem Cells as New therapeutic Targets for Ovarian CancerYinu Wang, Fang Fang, Salvatore Condello, Daniela Matei and Kenneth P. Nephew
Section III. CSC Features and Mechanisms
10. Understanding Cancer Cells of Origin in Cutaneous TumorsHyeongsun Moon, Leanne R. Donahue, Andrew C. White
11. Asymmetric Division of Cancer Stem CellsClaudia Petritsch and Xiling Shen
12. Metastasis and Metastatic Cells: A Historical Perspective and Current Analysis Kiera Rycaj and Dean G. Tang
13. Metastasis and Evasion from the Host Immune ResponsesAvijeet Chopra, Xia Liu, Huiping Liu
14. Cancer Stem Cells and Tumor Associated MacrophagesWenchao Zhou and Shideng Bao
15. The Mechanisms of Therapy Resistance in Cancer Stem CellsChi-Hsuan Chang and Jeffrey M. Rosen
16. Adipose tissue-derived stem cells in regenerative medicine and impact on cancerPraveena S. Thiagarajan, Justin D. Lathia, and Ofer Reizes
Section IV. Clinical Applications
17. From Research to the Clinic: Targeting Stem Cell Pathways in CancerAustin Gurney and Timothy Hoey
18. Targeted Therapies for Glioma Stem CellsSwetha J. Sundar, James Wright, Jason K. Hseih & Andrew E. Sloan
19. Circulating tumor cells, cancer stem cells, and emerging microfluidic detection technologies with clinical applicationsMolly Kozminsky and Sunitha Nagrath
1. Introduction: Cancer Stem Cells Siddhartha S. Mitra, Joy He, Rogelio Esparza, Gregor Hutter, Samuel H. Cheshier and Irving Weissman
2. Overview: Cancer Stem Cell Self-RenewalMaider Zabala, Neethan A. Lobo, Dalong Qian, Linda J. van Weele, Diane Heiser and Michael F. Clarke
3. Enrichment and Interrogation of Cancer Stem CellsAwad Jarrar, Anastasia Chumakova, Masahiro Hitomi, Justin Lathia
Section II. CSCs in Representative Organ systems
4. Critical Updates to the Leukemia Stem Cell ModelYogen Saunthararajah
5. Breast cancer stem cells and the move toward high resolution stem cell systemsBenjamin T. Spike
6. Lung Cancer Stem Cells: Drivers of Genetically and Histologically Complex DiseaseChristine M. Fillmore and Carla F. Kim
7. Colorectal cancer stem cellsSumaiyah Rehman, Jennifer Haynes, Evelyne Lima-Fernandes, Akshita Puri, Andrew Haller, Cherry Leung, Lauren Agro, Yadong Wang, and Catherine A. O’Brien
8. Targeting Bladder Cancer Stem Cells: One-Step Closer To The Clinic?Antonina Kurtova and Keith Syson Chan
9. Cancer Stem Cells as New therapeutic Targets for Ovarian CancerYinu Wang, Fang Fang, Salvatore Condello, Daniela Matei and Kenneth P. Nephew
Section III. CSC Features and Mechanisms
10. Understanding Cancer Cells of Origin in Cutaneous TumorsHyeongsun Moon, Leanne R. Donahue, Andrew C. White
11. Asymmetric Division of Cancer Stem CellsClaudia Petritsch and Xiling Shen
12. Metastasis and Metastatic Cells: A Historical Perspective and Current Analysis Kiera Rycaj and Dean G. Tang
13. Metastasis and Evasion from the Host Immune ResponsesAvijeet Chopra, Xia Liu, Huiping Liu
14. Cancer Stem Cells and Tumor Associated MacrophagesWenchao Zhou and Shideng Bao
15. The Mechanisms of Therapy Resistance in Cancer Stem CellsChi-Hsuan Chang and Jeffrey M. Rosen
16. Adipose tissue-derived stem cells in regenerative medicine and impact on cancerPraveena S. Thiagarajan, Justin D. Lathia, and Ofer Reizes
Section IV. Clinical Applications
17. From Research to the Clinic: Targeting Stem Cell Pathways in CancerAustin Gurney and Timothy Hoey
18. Targeted Therapies for Glioma Stem CellsSwetha J. Sundar, James Wright, Jason K. Hseih & Andrew E. Sloan
19. Circulating tumor cells, cancer stem cells, and emerging microfluidic detection technologies with clinical applicationsMolly Kozminsky and Sunitha Nagrath