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Carbohydrate–Based Vaccines and Immunotherapies: Wiley Series in Drug Discovery and Development

Autor Z Guo
en Limba Engleză Hardback – 2 iul 2009
The fundamental science and the latest developments in carbohydrate-based vaccines
The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments.
With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances.
Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include:
  • Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi
  • Using adjuvants to improve immunogenicity and/or immunological properties of vaccines
  • Choosing and designing proper adjuvants for specific targets
  • Abnormal carbohydrates expressed by tumors
  • Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy
  • Clinical trials results for synthetic cancer vaccines
  • Glycoengineering of cell surface carborhydrates and its anticancer applications
  • Using cell surface carbohydrates for disease diagnosis
A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.
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Specificații

ISBN-13: 9780470197561
ISBN-10: 0470197560
Pagini: 434
Dimensiuni: 164 x 238 x 29 mm
Greutate: 0.73 kg
Editura: Wiley
Seria Wiley Series in Drug Discovery and Development

Locul publicării:Hoboken, United States

Public țintă

Medicinal chemists, organic chemists (particularly carbohydrate and synthetic), biochemists, researchers, academics and government research libraries.  

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Descriere

Studies of vaccines derived from carbohydrate antigens have seen great progress. Synthetic carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids, have been explored or used to prevent and treat bacterial and viral infections, cancer, and other diseases.