Carbohydrate–Based Vaccines and Immunotherapies: Wiley Series in Drug Discovery and Development
Autor Z Guoen Limba Engleză Hardback – 2 iul 2009
The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments.
With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances.
Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include:
- Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi
- Using adjuvants to improve immunogenicity and/or immunological properties of vaccines
- Choosing and designing proper adjuvants for specific targets
- Abnormal carbohydrates expressed by tumors
- Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy
- Clinical trials results for synthetic cancer vaccines
- Glycoengineering of cell surface carborhydrates and its anticancer applications
- Using cell surface carbohydrates for disease diagnosis
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Specificații
ISBN-13: 9780470197561
ISBN-10: 0470197560
Pagini: 434
Dimensiuni: 164 x 238 x 29 mm
Greutate: 0.73 kg
Editura: Wiley
Seria Wiley Series in Drug Discovery and Development
Locul publicării:Hoboken, United States
ISBN-10: 0470197560
Pagini: 434
Dimensiuni: 164 x 238 x 29 mm
Greutate: 0.73 kg
Editura: Wiley
Seria Wiley Series in Drug Discovery and Development
Locul publicării:Hoboken, United States
Public țintă
Medicinal chemists, organic chemists (particularly carbohydrate and synthetic), biochemists, researchers, academics and government research libraries.Notă biografică
Cuprins
Descriere
Studies of vaccines derived from carbohydrate antigens have seen great progress. Synthetic carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids, have been explored or used to prevent and treat bacterial and viral infections, cancer, and other diseases.