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Cardiotoxicity of Chemotherapeutic Agents

Editat de Gregg Lanier, Jalaj Garg, Neeraj Shah
en Limba Engleză Paperback – 31 iul 2017
Cardiotoxicity is a well-established complication of antineoplastic agents. Cardiomyopathy resulting from anthracyclines is a classic example. In the past decade, an explosion of novel cancer therapies, often targeted and more specific than conventional therapies, has revolutionised oncology therapy and dramatically changed cancer prognosis. However, some of these therapies have introduced an assortment of cardiovascular complications. At times, these devastating outcomes have only become apparent after drug approval and have limited the use of potent therapies. There is a growing need for better testing platforms, both for cardiovascular toxicity screening and for elucidating mechanisms of cardiotoxicity of approved cancer therapies. Our book is a comprehensive summary of information of numerous antineoplastic agents and their cardiovascular adverse effects. Cardiac oncology is an exciting and ever-changing field, and we have attempted to synthesise information from all the major and relevant studies in the field in our book. The authors hope that their book serves as a valuable reference in the field of cardiac oncology for the clinicians who are actively involved in the management of patients receiving antineoplastic agents, including primary care physicians, cardiologists, cardiology fellows in training and oncologists.
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Specificații

ISBN-13: 9781536121193
ISBN-10: 1536121193
Pagini: 140
Dimensiuni: 155 x 230 x 17 mm
Greutate: 0.43 kg
Editura: Nova Science Publishers Inc
Colecția Nova Science Publishers Inc

Cuprins

Preface; Introduction: Cardiotoxicity of Chemotherapeutic Agents; Alkylating Agents; Antimetabolites; Antitumor Antibiotics: Bleomycin & Mitoxantrone; Antitumor Antibiotics: Anthracyclines, a Mechanism of Cardiotoxicity; Antitumor Antibiotics: Anthracyclines, Cardiotoxicity & Associated Risk Factors; Antitumor Antibiotics: Anthracyclines & Minimizing Cardiotoxicity; Antitumor Antibiotics: Newer Anthracyclines; Microtubule Inhibitors; Hormonal Therapy; Immunotherapy; Monoclonal Antibodies; Tyrosine Kinase Inhibitors; Topoisomerase-1 Inhibitors & Miscellaneous Drugs; Index.