"Case Studies" documents personal tragedies over the course of the twentieth century often pertaining to uncontrollable health ailments. At other times, these tragedies may or may not be at the hands of another. In either case, making the transition from healthy to unhealthy can be a difficult endeavor. This can take the form of physical damage to the brain structure, autism, Parkinson disease, spinal injury, multiple sclerosis, Alzheimer disease, or brain death. Read about these individuals' personal tragedies and how they learn to cope in dealing with these health concerns in his or her life. Many may take their health for granted, and many others as described here may have deserved a second chance.