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Characterization of Impurities and Degradants Using Mass Spectrometry de B Pramanik

Characterization of Impurities and Degradants Using Mass Spectrometry: Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods

Autor B Pramanik
en Limba Engleză Hardback – 9 mai 2011
The book highlights the current practices and future trends in structural characterization of impurities and degradants. It begins with an overview of mass spectrometry techniques as related to the analysis of impurities and degradants, followed by studies involving characterization of process related impurities (including potential genotoxic impurities), and excipient related impurities in formulated products. Both general practitioners in pharmaceutical research and specialists in analytical chemistry field will benefit from this book that will detail step-by-step approaches and new strategies to solve challenging problems related to pharmaceutical research.
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Specificații

ISBN-13: 9780470386187
ISBN-10: 0470386185
Pagini: 496
Dimensiuni: 159 x 241 x 30 mm
Greutate: 0.66 kg
Editura: Wiley
Seria Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods

Locul publicării:Hoboken, United States

Public țintă

Pharmaceutical scientists and researchers in drug metabolism, analytical research, and pharmaceutical development, process chemists, bioanalytical chemists

Cuprins

Notă biografică

BIRENDRA N. PRAMANIK is a Distinguished Fellow at Merck Research Laboratories, where he directs spectroscopy programs covering mass spectrometry and NMR efforts. He was previously a distinguished fellow at Schering-Plough Research Institute. He received his PhD in organic chemistry under the late Professor Ajay K. Bose from Stevens Institute of Technology in 1977. MIKE S. LEE is President of Milestone Development Services, a provider of consulting services specializing in pharmaceutical analysis and accelerated drug discovery and development strategies in Newtown, Pennsylvania. He previously directed program research at Bristol-Myers Squibb, Pharmaceutical Research Institute in New Brunswick, New Jersey. GUODONG CHEN is Principal Scientist in Bioanalytical and Discovery Analytical Sciences at Bristol-Myers Squibb in Princeton, New Jersey. He heads a mass spectrometry group in support of drug discovery as well as development programs in small molecule pharmaceuticals and biologics. He received his PhD in analytical chemistry from Purdue University under the direction of Professor R. Graham Cooks.

Descriere

The book highlights the current practices and future trends in structural characterization of impurities and degradants.