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Chondrosarcoma: Biology and Clinical Management

Editat de Francis J. Hornicek
en Limba Engleză Paperback – 18 iun 2021
Chondrosarcoma, a rare cancer that develops from cartilage cells, occurs mainly in the bones but can also appear in the soft tissue of the pelvis, hip and shoulder. Unfortunately, these cancers are highly resistant to both chemotherapy and radiation, and no successful adjuvant therapies currently exist. As such, surgical treatment and resection remain the mainstays of management for patients with these tumors.
This concise text is a comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas. Part I discusses pathology, molecular biology and imaging features of chondrosarcomas. The different types of skeletal and extraskeletal tumors are presented in detail in part II, including conventional and secondary tumors. Management approaches are outlined and described in part III - limb salvage surgery is the most common, and although less effective, radiation and chemotherapy are indicated in certain cases. Part IV examines the future of chondrosarcoma management and development of novel adjuvant therapies, as well as the relationship of this disease to similar types (e.g., chordoma).
 Bringing together the most up-to-date information on this rare cancer, Chondrosarcoma will be a valuable resource for orthopedic oncologists, researchers and all medical professionals treating these challenging tumors. 

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Specificații

ISBN-13: 9783030745714
ISBN-10: 3030745716
Pagini: 304
Ilustrații: XVII, 304 p. 64 illus., 35 illus. in color.
Dimensiuni: 127 x 203 mm
Greutate: 0.41 kg
Ediția:1st ed. 2021
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Part I. Biology of Chondrosarcoma.- Pathology of Chondrosarcoma.- Advances in the Molecular Biology of Chondrosarcoma.- Imaging Features of Chondrosarcoma.- Part II. Skeletal and Extraskeletal Chondrosarcoma.- Chondrosarcomas: Conventional and Secondary.- Primary Soft Tissue Chondrosarcoma.- Part III. Management of Chondrosarcoma.- Chondrosarcoma of the Axial Skeleton.- Chondrosarcoma of the Appendicular Skeleton.- Chondrosarcoma of the Hand.- Chondrosarcoma of the Clavicle.- Radiation Therapy for Chondrosarcoma.- Systemic Therapy for Chondrosarcoma.- Vascular Issues in Complex Surgical Resection of Chondrosarcoma.- Part IV. The Future of Chondrosarcoma Research and Treatment.- The Future of Chondrosarcoma Research and Treatment.

Notă biografică


Francis John Hornicek, M.D., Ph.D.
Professor and Chair
Department of Orthopaedic Surgery
Helga and Walter Oppenheimer Endowed Chair in Orthopaedic Oncology
David Geffen School of Medicine at UCLA
10833 Le Conte Ave, 76-143 CHS Los Angeles, CA 



Textul de pe ultima copertă

Chondrosarcoma, a rare cancer that develops from cartilage cells, occurs mainly in the bones but can also appear in the soft tissue of the pelvis, hip and shoulder. Unfortunately, these cancers are highly resistant to both chemotherapy and radiation, and no successful adjuvant therapies currently exist. As such, surgical treatment and resection remain the mainstays of management for patients with these tumors.
This concise text is a comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas. Part I discusses pathology, molecular biology and imaging features of chondrosarcomas. The different types of skeletal and extraskeletal tumors are presented in detail in part II, including conventional and secondary tumors. Management approaches are outlined and described in part III - limb salvage surgery is the most common, and although less effective, radiation and chemotherapy are indicated in certain cases. Part IV examines the future of chondrosarcoma management and development of novel adjuvant therapies, as well as the relationship of this disease to similar types (e.g., chordoma).
 Bringing together the most up-to-date information on this rare cancer, Chondrosarcoma will be a valuable resource for orthopedic oncologists, researchers and all medical professionals treating these challenging tumors. 

Caracteristici

A concise, comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas Describes in detail the biology, types and management of chondrosarcoma, with a focus on surgical approaches Excellent for orthopedic oncologists and researchers working with these challenging tumors