Although Clinical alarm systems at the Critical Care Settings are proposed to alert caregivers of potential patients' problems it produce a noise environment that induce momentous negative alterations in the patients' health and safety especially if ignored or desensitized as a re-sult of overwhelming, This book aims at highlighting the clinical alarms in the Critical Care Settings and associated hazards to the patients and caregivers in addition to suggest clinical solutions and identify advanced systems that may be solving these problems. ECRI Institute scheduled alarm hazards as the number one issue of its annual list of the top 10 health-technology dangers since 2014. In fact almost of alarms in Critical Care Settings considered as a false alarms (has no clinical significant) so the author aiming at finding evidenced based strategies to preventing these false alarms and consequently minimizing the entire alarms in Critical Care Setting and it's hazards.