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Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation

Editat de Beth Devine, Richard David Boyce, Kristin Wiisanen
en Limba Engleză Paperback – 20 iun 2022
Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation offers overviews, methods and strategies for translating genomic medicine to clinical practice. The book's authors explore incorporating pharmacogenetics into electronic health records, CDS methods and infrastructure for delivery, economic evaluation, the hospital administrations’ role and needs in integration, and patient counseling aspects. The book empowers clinicians, researchers, translational scientists, and data and IT experts to effectively navigate the complex landscape of CDS for pharmacogenomic precision medicine. Illustrative case studies of existing gene networks include CSER, eMERGE, the IGNITE network, DIGITIZE, the CDS Learning Network (RTI), ClinGen, Ubiquitous and CDS Hooks.

  • Offers an applied, case-driven discussion of CDS for pharmacogenomic precision medicine
  • Illustrates key concepts, contemporary developments, and future directions using examples of existing gene networks
  • Features contributions from leading voices in precision medicine and clinical decision support
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Specificații

ISBN-13: 9780128244531
ISBN-10: 0128244534
Pagini: 296
Ilustrații: 80 illustrations (40 in full color)
Dimensiuni: 152 x 229 x 22 mm
Greutate: 0.4 kg
Editura: ELSEVIER SCIENCE

Public țintă

Active researchers, basic and translational scientists, and IT professionals in the areas of human genomics, bioinformatics, pharmacology, prenatal testing, and electronic healthcare records; genetic counselors; hospital administrators

Cuprins

SECTION 1 Foundations of Clinical Decision Support and Pharmacogenomic Precision Medicine
1. Overview of Effective Pharmacogenomic Clinical Decision Support
2. Scientific Evidence and Sources of Knowledge for Pharmacogenomics
3. Laboratory Considerations for Pharmacogenomic Clinical Decision Support
4. Ensuring Equity and Access to Pharmacogenomic Clinical Decision Support
SECTION 2 Developing and Building Clinical Decision Support for Pharmacogenomic Precision Medicine
5. Clinical Decision Support Methods and Infrastructure
6. Deep Phenotyping and Machine Learning to Target Drug Therapies
7. Usability and Human-Centered Design
8. Clinical Considerations for Clinical Decision Support
SECTION 3 Adoption and Delivery of Clinical Decision Support for Pharmacogenomic Precision Medicine
9. Patient-Facing Clinical Decision Support for Pharmacogenomic Precision Medicine
10. Role of the Genetic Counselor in Pharmacogenomic Precision Medicine
11. A Learning Health System Approach to Delivery and Adoption of Clinical Decision Support
12. Integration of Clinical Decision Support Infrastructure and Translating into Real-World Applications