The book "Compilado de artigos sobre pessoas que vivem com o HIV: assistência integral à saúde da criança, da mulher e do adolescente" describes the articles produced at the Ambulatório Escola (Ambes) on this subject, with their respective protocols. Ambes is considered a Regional Reference Centre for the Prevention and Treatment of STIs, HIV/Aids and Viral Hepatitis and serves as a field for practical classes and internships for students from various undergraduate courses. The existence of vertical transmission of HIV alerts us to the need to look at systematising practices related to maternal and child care in the context of maternal HIV seropositivity, which can be helped by building a comprehensive care protocol for maternal and child clients, based on public policy proposals for this clientele, and on the health team's reflection and discussion on the proposed actions, according to real needs and feasibility. A protocol for women's and adolescents' health care is also needed, as these are a group susceptible to HIV infection.