The development of cancer from the rectum or the colon is termed as colorectal cancer. It originates in the epithelial cells. It generally occurs due to factors related to lifestyle or old age. Its major symptoms are blood in the stool, fatigue, weight loss and a change in bowel movements. It might begin as a benign tumor, and could become cancerous as time passes. It can be diagnosed through a colonoscopy or a sigmoidoscopy. The treatment of colorectal cancer is done through various methods such as radiation therapy, chemotherapy, surgery, targeted therapy, etc. There are various methods of reducing the risk of colorectal cancer such as through exercise, quitting smoking and reducing alcohol intake. The objective of this book is to give a general view of the diagnosis and management of colorectal cancer. It brings forth some of the most innovative concepts and elucidates the unexplored aspects of research on this disease. The book is appropriate for students seeking detailed information in this area as well as for experts.