This book constitutes the revised selected papers of the First International Conference, ICCSST 2023, held in Bangalore, India, during May 8–9, 2023. The 39 full papers included in this volume were carefully reviewed and selected from 200 submissions. They focus on artificial intelligence, blockchain technology, cloud computing, cyber security, data science, e-commerce, computer architecture, image and video processing, pandemic preparedness and digital technology, pattern recognition and classification.