Contemporary Topics in Critical Care Medicine

SECTION 1: Airway Management — Current Controversies
1. Can Sellick Maneuver Prevent Pulmonary Aspiration in the Critically Ill?
2. Etomidate vs. Ketamine — What Should We Use for Intubation in ICU
SECTION 2: Extracorporeal Therapies
3. Plasmapheresis: Current Indications in the Critically Ill
4. Are Super High-Flux Membrane Dialyzers the Future of RRT?
5. What is New in Artificial Liver Support Systems?
SECTION 3: Sepsis
6. Back to the Genes: Does Genetic Polymorphism have a Role in Sepsis Management?
7. Controversies in Surviving Sepsis Guidelines 2021
8. Are We Back to Square One? Early Fluids vs. Vasopreressors in Septic Shock
9. Have We Achieved Balance in Fluid Therapy: Balanced Salt Solutions vs. Normal Saline?
SECTION 4: Biomarkers
10. Novel Biomarkers During Circulatory Shock
11. Biomarkers in Acute Intoxications
12. Do Biomarkers have a Role in Patients with Primary Brain Injury?
13. Utility of MicroRNAs in the Critically Ill
14. Neutrophil to Lymphocyte Ratio in Critically Ill: A Simple but Useful Marker?
15. Do Vocal Biomarkers have a Future in Critical Care
SECTION 5: COVID-19 Pandemic: Lessons Learnt
16. Awake Prone Positioning in ARDS?
17. Immunomodulators for COVID-19 Therapy
18. Has Critical Care Telemedicine Come of Age During the Pandemic
19. Post-COVID Conditions (PCCs) or Long COVID Syndrome
20. Capacity Building During Large Scale Disasters
21. Clearing the Air: Alternatives to Isolation Rooms
SECTION 6: Mechanical Ventilation
22. Revisiting Exogenous Surfactant Therapy in Acute Lung Injury and ARDS
23. Mechanical Power
24. Volumetric Capnography in 2022
25. Metabolic Alkalosis in Critical Care: A Classical and Physicochemical Approach
26. Oxygen Revisited
SECTION 7
28. High-flow Nasal Cannula: Beyond a COVID-19 Therapy
29. Cefiderocol
30. Newer Fluoroquinolones: Levonadifloxacin, Delafloxacin and Lascufloxacin
31. Newer Combinations of B-Lactam/B-Lactamase
32. Newer Tetracyclines — Eravacycline and Omadacycline
33. Plazomicin: A New Aminoglycoside
34. Lefamulin: A Pleuromutilin Antibiotic
35. Pretomanid for Antitubercular Therapy
36. Contezolid Acefosamil: A New Oxazolidinone
37. Solithromycin and Nafithromycin: The New Macrolides
38. Benapenem and Sulopenem
39. The Dsb (Disulfide bond)
40. Antivirulence Strategies: The Future of Antibacterial Therapy
41. Alternatives to Conventional Antibacterials: Use of Nanomaterials
42. Newer Treatment Approach to Clostridioides Difficile – Fidaxomicin and Bezlotoxumab
43. Recent Advances for Immunotherapies Against Infectious Disease
SECTION 8: What's New Elsewhere?
44. Risk Scoring Systems in Upper Gastrointestinal Bleed
45. Has Hypotension Prediction Index Come of Age
46. Postintensive Care Syndrome and Postintensive Care Syndrome-Family
47. Closed-Loop Hemodynamic Resuscitation In Shock
48. Is Electrical Impedance Tomography Finally Here to Stay
49. Cardiac Output Measurement: Capnodynamic Method and Auto VTI Tool
50. What’s New in Glucose Management Technologies for the Critically-ill
51. Vitamins and Trace Element Supplementation for Critically Ill Patients in 2022
Index

Atul P Kulkarni MD (Anaesthesiology) FISCCM PGDHHM FICCM
Professor and Head, Division of Critical Care Medicine, Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India
Ross Callum Freebairn MBChB Dip Obst FANZCA FRCPE FJFICMI(Hon) FCICM
Consultant and Associate Dean, Intensive Care Medicine, Hawke’s Bay Hospital, Hastings New Zealand; School of Medicine, University of Otago Hastings, New Zealand
Subhash P Acharya MD (Anaesthesiology) Fellowship in Adult Critical Care (FACC, University of Toronto)
Professor and Head, Department of Critical Care Medicine, Maharjgunj Medical Campus, Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Nepal