The world as we know it today is made of collective innovation accumulated through millions of years and copied, improved, and scaled by successive civilizations and dynasties. Innovation tends to take place in an ecosystem where the entrepreneurial spirit is prevalent, with access to good research institutions and ample funding, enabling a vibrant collaboration between individuals that foster innovation. The university system in America is unusual among industrialized countries to have a long history of interaction with the commercial corporation "The Industry", where many of the innovative activities within universities rely on the input of both ideas and people along with generous financial support. Such interactions are very rare in Europe, Japan, or most developing countries, but are becoming common gradually. This book is about bringing clarity and transparency into the knowledge economy and helping accelerate its evolution further, by democratizing innovation execution and thought leadership, accessing actionable insights to level the playing field and help shape the current and future generation of innovators from across the world on how to execute incremental improvement to the human lives and solve pressing global challenges of our times.