Ex-cop and Native American private investigator Noel Two Horses is hired by a well-to-do madame to help clear her decorated Navy corpsman kid-brother who has been recently discharged from the Navy and is now framed for the murder of a Phoenix, Arizona stripper. Two Horses soon discovers he needs to protect his client from his older sister who framed him for the murder. Her estranged family members lived with her dysfunction, power playing, and lying until she was a teenager, and she left home returning to her native Columbia to lead an adult-criminal lifestyle. Supported by illicit drug money and organized cartels, the sister stalks both Two Horses and her brother to silence them.