It is 1905 and Chicago is an open town. The most open part of town is the Levee District. It is an area of the city that's hard to tell the crooks from the cops. There are brothels, madams, opium dens, gambling joints and plenty of alcohol, but it all comes at a price in the Levee, and the two Ward Aldermen get their share of every vice's dollar. With the hanging of serial killer, Simon Kluge, police Detective Patrick Moses is suddenly without a case. Before Moses can relax he is approached by an aging retail mogul who asks him to investigate the mysterious shooting death of his son. Moses accepts the offer and at the same time is asked by the department to search for the niece of the Italian Ambassador who has gone missing in the Levee and is suspected of becoming a victim of Chicago's "white slave" traffic, forced into a life of enslaved prostitution. As Moses gets deeper into both cases, he realizes that in the Levee there are a lot people who don't want the two cases solved, including the police and the Ward Aldermen. Soon a number of sources and witnesses end up murdered. Someone wants Moses and his partner, Gunter Krause, dead. On top of that, trinkets from the Simon Kluge murders begin to appear on Moses' doorstep, leading him to believe they may have executed the wrong person.