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CRISPR Genome Surgery in Stem Cells and Disease Tissues

Editat de Stephen H. Tsang
en Limba Engleză Paperback – 18 oct 2021
CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature.


  • Provides a thorough review of CRISPR-Cas9, from discovery to therapy
  • Covers the latest advances in gene editing and its translational applications to various diseases
  • Written by global leaders in the fields of gene editing and stem cell therapy
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Specificații

ISBN-13: 9780128178768
ISBN-10: 0128178760
Pagini: 136
Ilustrații: 25 illustrations (15 in full color)
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE

Public țintă

Scientists involved in stem cell engineering and gene editing, and individuals of any medical subspecialty

Cuprins

1. History of CRISPR 2. Different Kinds of CRISPR (SpCas9, CjCas9, CaCas9, etc.) 3. Genome engineering in iPSC cells 4. CRISPR manipulations in stem cell lines for neurological diseases 5. Gene editing for the cornea 6. CRISPR screening for eye diseases 7. Employing Non-homologous End Joining and Homology-directed Repair for Treatment of Leber Congenital Amaurosis and Retinal Degeneration 8. Ethics of Gene Editing in Human Stem Cells 9. sGRNA 10. CRISPR vs ZFN/TALEN