Lizzy Zubiaga, queen of synthetic drugs, plans to create an international bank for high-level criminals. The road is not without obstacles: first, a commando kidnaps Oscar Salgado, owner of a brokerage house, to steal financial information from Lizzy. Then, Andrea Mijanos, now retired from the Judicial Police, returns as a private detective and is assigned to new cases without ever losing sight of the cartel. Lizzy and Andrea are bound to cross paths again.